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Abnormality iris morphology

MedGen UID:
871351
Concept ID:
C4025845
Anatomical Abnormality
Synonym: Iris abnormalities
 
HPO: HP:0000525

Definition

An abnormality of the iris, which is the pigmented muscular tissue between the cornea and the lens, that is perforated by an opening called the pupil. [from HPO]

Professional guidelines

PubMed

Cassart M
Pediatr Radiol 2023 Apr;53(4):610-620. Epub 2022 Jul 16 doi: 10.1007/s00247-022-05433-4. PMID: 35840694
Yu X, Chen W, Xu W
J Cataract Refract Surg 2020 Dec;46(12):1674-1679. doi: 10.1097/j.jcrs.0000000000000334. PMID: 32694307
Stefan C, Iliescu DA, Batras M, Timaru CM, De Simone A
Rom J Ophthalmol 2015 Jan-Mar;59(1):14-8. PMID: 27373109Free PMC Article

Recent clinical studies

Etiology

van Velthoven AJH, Utheim TP, Notara M, Bremond-Gignac D, Figueiredo FC, Skottman H, Aberdam D, Daniels JT, Ferrari G, Grupcheva C, Koppen C, Parekh M, Ritter T, Romano V, Ferrari S, Cursiefen C, Lagali N, LaPointe VLS, Dickman MM
Surv Ophthalmol 2023 Sep-Oct;68(5):940-956. Epub 2023 May 4 doi: 10.1016/j.survophthal.2023.04.003. PMID: 37146692
Venkataraman P, Haripriya A, Mohan N, Rajendran A
Indian J Ophthalmol 2022 Jul;70(7):2262-2271. doi: 10.4103/ijo.IJO_2888_21. PMID: 35791105Free PMC Article
Ebrahimiadib N, Maleki A, Fadakar K, Manhapra A, Ghassemi F, Foster CS
Surv Ophthalmol 2021 Jul-Aug;66(4):653-667. Epub 2021 Jan 5 doi: 10.1016/j.survophthal.2020.12.006. PMID: 33412171
Suthers G, David D, Clark B
Clin Dysmorphol 1997 Jul;6(3):245-9. doi: 10.1097/00019605-199707000-00008. PMID: 9220195
Zellweger H, Ionasescu V, Simpson J
J Genet Hum 1975 Mar;23(1):65-75. PMID: 1165480

Diagnosis

Casas-Llera P, Ruiz-Casas D, Alió JL
Arch Soc Esp Oftalmol (Engl Ed) 2021 Nov;96 Suppl 1:60-67. Epub 2021 Jun 4 doi: 10.1016/j.oftale.2020.11.006. PMID: 34836590
Jeeva-Patel T, Lutchman C, Margolin E
Ophthalmology 2021 Apr;128(4):586. doi: 10.1016/j.ophtha.2020.11.006. PMID: 33745527
Bouffard MA
Continuum (Minneap Minn) 2019 Oct;25(5):1194-1214. doi: 10.1212/CON.0000000000000771. PMID: 31584534
Stefan C, Iliescu DA, Batras M, Timaru CM, De Simone A
Rom J Ophthalmol 2015 Jan-Mar;59(1):14-8. PMID: 27373109Free PMC Article
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938

Therapy

Agarwal A, Narang P, Narang R
Indian J Ophthalmol 2022 Oct;70(10):3745-3746. doi: 10.4103/ijo.IJO_1630_22. PMID: 36190103Free PMC Article
Venkataraman P, Haripriya A, Mohan N, Rajendran A
Indian J Ophthalmol 2022 Jul;70(7):2262-2271. doi: 10.4103/ijo.IJO_2888_21. PMID: 35791105Free PMC Article
Del Hierro Zarzuelo A, Boto de Los Bueis A
Arch Soc Esp Oftalmol 2016 Sep;91(9):422-5. Epub 2016 Mar 17 doi: 10.1016/j.oftal.2016.02.005. PMID: 26996049
Li J, Tripathi RC, Tripathi BJ
Drug Saf 2008;31(2):127-41. doi: 10.2165/00002018-200831020-00003. PMID: 18217789
Farrar SM, Shields MB
Surv Ophthalmol 1993 Jan-Feb;37(4):233-52. doi: 10.1016/0039-6257(93)90008-u. PMID: 8095105

Prognosis

Kruijt CC, de Wit GC, Bergen AA, Florijn RJ, Schalij-Delfos NE, van Genderen MM
Ophthalmology 2018 Dec;125(12):1953-1960. Epub 2018 Aug 8 doi: 10.1016/j.ophtha.2018.08.003. PMID: 30098354
Mahmoudi A, Rami M, Khattala K, Elmadi A, Afifi MA, Youssef B
Pan Afr Med J 2013;14:60. Epub 2013 Feb 12 doi: 10.11604/pamj.2013.14.60.1543. PMID: 23565307Free PMC Article
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938
Ritch R, Schlötzer-Schrehardt U
Surv Ophthalmol 2001 Jan-Feb;45(4):265-315. doi: 10.1016/s0039-6257(00)00196-x. PMID: 11166342
Pagon RA
Surv Ophthalmol 1981 Jan-Feb;25(4):223-36. doi: 10.1016/0039-6257(81)90092-8. PMID: 6782689

Clinical prediction guides

Sihota R, Mahalingam K, Maurya AK, Sharma A, Bukke AN, Dada T
Indian J Ophthalmol 2024 Mar 1;72(3):328-334. Epub 2023 Dec 15 doi: 10.4103/IJO.IJO_370_23. PMID: 38099353Free PMC Article
Elbaz U, Ali A, Strungaru H, Mireskandari K
Cornea 2022 Feb 1;41(2):192-200. doi: 10.1097/ICO.0000000000002768. PMID: 34176915
Kruijt CC, de Wit GC, Bergen AA, Florijn RJ, Schalij-Delfos NE, van Genderen MM
Ophthalmology 2018 Dec;125(12):1953-1960. Epub 2018 Aug 8 doi: 10.1016/j.ophtha.2018.08.003. PMID: 30098354
Del Hierro Zarzuelo A, Boto de Los Bueis A
Arch Soc Esp Oftalmol 2016 Sep;91(9):422-5. Epub 2016 Mar 17 doi: 10.1016/j.oftal.2016.02.005. PMID: 26996049
Li CQ, Cho AA, Edward NJ, Edward DP, Fajardo RG, Mafee MF
Neuroradiology 2015 Aug;57(8):825-32. Epub 2015 Apr 24 doi: 10.1007/s00234-015-1531-7. PMID: 25903430

Recent systematic reviews

Chen ZX, Jia WN, Sun Y, Chen TH, Zhao ZN, Lan LN, Liu Y, Song LH, Jiang YX
Hum Mutat 2022 Dec;43(12):2141-2152. Epub 2022 Oct 17 doi: 10.1002/humu.24483. PMID: 36208099
Li X, Sun W, Xiao X, Fang L, Li S, Liu X, Zhang Q
Br J Ophthalmol 2022 Dec;106(12):1710-1715. Epub 2021 Jun 21 doi: 10.1136/bjophthalmol-2020-318668. PMID: 34154991
Yu X, Chen W, Xu W
J Cataract Refract Surg 2020 Dec;46(12):1674-1679. doi: 10.1097/j.jcrs.0000000000000334. PMID: 32694307
Stefan C, Iliescu DA, Batras M, Timaru CM, De Simone A
Rom J Ophthalmol 2015 Jan-Mar;59(1):14-8. PMID: 27373109Free PMC Article
Martins AC, Rosa AM, Costa E, Tavares C, Quadrado MJ, Murta JN
Biomed Res Int 2015;2015:282405. Epub 2015 Oct 19 doi: 10.1155/2015/282405. PMID: 26558262Free PMC Article

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